Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31404219 | 0.86 | TAAR1 (0.61) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL256694 | 0.81 | TAAR1 (0.62) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL7929109 | 0.79 | TAAR1 (0.61) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL1145952 | 0.79 | HTR2A (0.56) | TAAR1HTR2CHTR2AHTR2BMIF | |
| SCHEMBL11383498 | 0.79 | TAAR1 (0.65) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL28260251 | 0.78 | TAAR1 (0.59) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL28261580 | 0.78 | TAAR1 (0.59) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL2094737 | 0.78 | TAAR1 (0.59) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL28143319 | 0.78 | TAAR1 (0.59) | TAAR1HTR2CHTR2AHTR2BHDAC1 | |
| SCHEMBL1045499 | 0.77 | TAAR1 (0.62) | TAAR1HTR2CHTR2AHTR2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417111-A1 | SUBSTITUTED 1-ALKYLCINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION OF SAME | SANOFI (FR) | 2012-02-15 | — | — | EP | disclosed |