Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 19/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879397 | 0.93 | OPRD1 (0.67) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879405 | 0.91 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879320 | 0.90 | OPRD1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879344 | 0.87 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879372 | 0.87 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5490804 | 0.86 | OPRD1 (0.85) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879381 | 0.85 | OPRD1 (0.63) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879362 | 0.85 | OPRD1 (0.73) | OPRD1OPRM1OPRK1CHRM2CHRM3 | |
| SCHEMBL5879378 | 0.85 | OPRD1 (0.58) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879359 | 0.83 | OPRD1 (0.65) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064137-B2 | Analgesics; anxiolytic agents; gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-06-20 | — | — | US | claimed |