Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476056 | 0.90 | AKR1C3 (0.46) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| Acrylonitrile SCHEMBL1275059 | 0.87 | MCL1 (0.50) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| SCHEMBL693055 | 0.86 | AKR1C3 (0.59) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| SCHEMBL16462 | 0.86 | AKR1C3 (0.59) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| SCHEMBL10454886 | 0.86 | AKR1C3 (0.59) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| Methacrylic Acid SCHEMBL6906597 | 0.85 | CYP3A4 (0.46) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| Methacrylic Acid SCHEMBL437865 | 0.85 | CYP3A4 (0.46) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| Butadiene SCHEMBL5964914 | 0.85 | AKR1C3 (0.41) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| SCHEMBL9862581 | 0.85 | AKR1C3 (0.41) | MCL1LMNAALDH1A1KDM4EAKR1C3 | |
| SCHEMBL476359 | 0.85 | AKR1C3 (0.41) | MCL1LMNAALDH1A1KDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153899-B2 | Molding composition including an impact modifier derived from a silicone rubber monomer, a branched acrylate rubber such as isooctyl acrylate, and a graft link monomer; moldings with outdoor applications such as building materials | GENERAL ELECTRIC COMPANY (US) | 2006-12-26 | — | — | US | claimed |
| JP-2006518003-A | — | — | 2006-08-03 | — | — | JP | claimed |
| EP-1611187-A1 | SILICON-ACRYLATE IMPACT MODIFIER | GENERAL ELECTRIC COMPANY (US) | 2006-01-04 | — | — | EP | claimed |
| US-20050010001-A1 | Silicone-acrylate impact modifier and method for their preparation | GENERAL ELECTRIC COMPANY | 2005-01-13 | — | — | US | claimed |
| WO-2004074349-A1 | SILICON-ACRYLATE IMPACT MODIFIER | GENERAL ELECTRIC COMPANY (US) | 2004-09-02 | — | — | WO | claimed |
| US-20040162399-A1 | impact modifier composition comprises structural units derived from: at least one silicone rubber monomer, a branched acrylate rubber monomer | GENERAL ELECTRIC COMPANY | 2004-08-19 | — | — | US | claimed |
| US-7153899-B2 | Molding composition including an impact modifier derived from a silicone rubber monomer, a branched acrylate rubber such as isooctyl acrylate, and a graft link monomer; moldings with outdoor applications such as building materials | GENERAL ELECTRIC COMPANY (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1611187-A1 | SILICON-ACRYLATE IMPACT MODIFIER | GENERAL ELECTRIC COMPANY (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20050010001-A1 | Silicone-acrylate impact modifier and method for their preparation | GENERAL ELECTRIC COMPANY | 2005-01-13 | — | — | US | disclosed |
| WO-2004074349-A1 | SILICON-ACRYLATE IMPACT MODIFIER | GENERAL ELECTRIC COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |
| US-20040162399-A1 | impact modifier composition comprises structural units derived from: at least one silicone rubber monomer, a branched acrylate rubber monomer | GENERAL ELECTRIC COMPANY | 2004-08-19 | — | — | US | disclosed |