SCHEMBL476359

SCHEMBL476359

CCC=C(C)C(=O)O.N#CC=CC=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.41
MCL1 Q07820 2/20 0.40
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAOB P27338 3/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
LMNA P02545 4/20 0.36
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419752 0.87 TDP1 (0.40) AKR1C3MCL1GLATDP1MAOB
SCHEMBL476056 0.86 AKR1C3 (0.46) AKR1C3MCL1GLATDP1MAOB
SCHEMBL5879478 0.85 MCL1 (0.49) AKR1C3MCL1GLATDP1MAOB
SCHEMBL25276523 0.82 MGLL (0.40) AKR1C3MCL1GLATDP1MAOB
Juarezic Acid SCHEMBL3276072 0.82 HDAC3 (0.47) AKR1C3GLATDP1MAOBHDAC3
Methacrylic Acid SCHEMBL437865 0.81 CYP3A4 (0.46) AKR1C3MCL1GLATDP1MAOB
Methacrylic Acid SCHEMBL6906597 0.81 CYP3A4 (0.46) AKR1C3MCL1GLATDP1MAOB
Butadiene SCHEMBL5964914 0.81 AKR1C3 (0.41) AKR1C3MCL1GLATDP1MAOB
SCHEMBL9862581 0.81 AKR1C3 (0.41) AKR1C3MCL1GLATDP1MAOB
Bicarbonate SCHEMBL16751853 0.81 MAOB (0.54) MCL1GLATDP1MAOBHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094746-B1 THERMOPLASTIC RESIN HAVING UNIFORM COMPOSITION AND NARROW MOLECULAR WEIGHT DISTRIBUTION, AND METHOD FOR PREPARING THE SAME CHEIL IND INC (KR) 2012-02-01 EP disclosed