Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FER | P16591 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442104 | 0.87 | LRRK2 (0.43) | POLBALDH1A1MAPTIDO1LMNA | |
| SCHEMBL6952027 | 0.81 | POLB (0.50) | POLBALDH1A1MAPTIDO1MEN1 | |
| SCHEMBL4402923 | 0.81 | POLB (0.71) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30341829 | 0.81 | POLB (0.71) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21282101 | 0.80 | POLB (0.47) | POLBALDH1A1MAPTIDO1LMNA | |
| SCHEMBL6904886 | 0.79 | POLB (0.59) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL28751074 | 0.79 | POLB (0.69) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6307676 | 0.75 | POLB (0.54) | POLBALDH1A1MAPTLMNAHTT | |
| SCHEMBL7513257 | 0.73 | LRRK2 (0.52) | ALDH1A1MAPTIDO1LMNATGM2 | |
| SCHEMBL16385898 | 0.73 | LRRK2 (0.52) | POLBALDH1A1MAPTIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |