Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.62 |
| ▸ | MMP9 | P14780 | 4/20 | 0.62 |
| ▸ | MMP8 | P22894 | 4/20 | 0.62 |
| ▸ | MMP13 | P45452 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440551 | 0.83 | BCHE (0.61) | MMP2MMP9MMP8MMP13KDM4E | |
| SCHEMBL7430166 | 0.79 | KDM4E (0.63) | MMP2MMP9MMP8MMP13KDM4E | |
| SCHEMBL10454789 | 0.78 | HTT (0.76) | GAASMN1; SMN2LMNA | |
| SCHEMBL7430161 | 0.77 | TNKS (0.58) | MMP2MMP9MMP8MMP13KDM4E | |
| SCHEMBL4702843 | 0.76 | NPC1 (0.69) | MMP2MMP9MMP8MMP13KDM4E | |
| SCHEMBL2617472 | 0.76 | NPC1 (0.66) | MMP2MMP9MMP8MMP13KDM4E | |
| SCHEMBL4702840 | 0.76 | KDM4E (0.59) | MMP2MMP9MMP8MMP13KDM4E | |
| SCHEMBL1728418 | 0.75 | CNR1 (0.59) | MMP2KMT2AGAALMNA | |
| SCHEMBL2178266 | 0.75 | NPC1 (0.88) | MMP2MMP9MMP8KDM4EALDH1A1 | |
| SCHEMBL29386825 | 0.75 | NPC1 (0.88) | MMP2MMP9MMP8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |