SCHEMBL5879599

SCHEMBL5879599

O=C(O)CC1c2cscc2C(=O)N(CC(=O)NCc2ccc(Nc3nc4ccccc4[nH]3)cc2)c2ccccc21

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.85
ITGAV P06756 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5879629 0.95 ITGB3 (0.76) ITGB3ITGAV
SCHEMBL5879526 0.86 ITGB3 (0.88) ITGB3ITGAV
SCHEMBL5025374 0.79 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5028419 0.79 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5028370 0.79 ITGB3 (1.00) ITGB3ITGAV
Hydrochloric Acid SCHEMBL5879699 0.79 ITGB3 (0.98) ITGB3ITGAV
SCHEMBL5879538 0.79 ITGB3 (0.73) ITGB3ITGAV
SCHEMBL5879616 0.77 ITGB3 (0.71) ITGB3ITGAV
SCHEMBL5879713 0.76 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5025473 0.75 ITGB3 (0.88) ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105508-B1 Integrin receptors antagonists ABBOTT GMBH & CO. KG (DE) 2006-09-12 US disclosed