SCHEMBL5879624

SCHEMBL5879624

Cc1cc2nc(-c3ccc(CNC(=O)CN4C(=O)c5ccccc5C(CC(=O)O)c5ccccc54)cc3)[nH]c2cc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 1.00
ITGAV P06756 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5879699 0.89 ITGB3 (0.98) ITGB3ITGAV
SCHEMBL5879849 0.89 ITGB3 (0.89) ITGB3ITGAV
SCHEMBL5879577 0.80 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5879713 0.80 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5879678 0.79 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5879584 0.78 ITGB3 (0.73) ITGB3ITGAV
SCHEMBL13790953 0.76 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5879550 0.75 ITGB3 (0.73) ITGB3ITGAV
SCHEMBL5879843 0.75 ITGB3 (1.00) ITGB3ITGAV
SCHEMBL5879551 0.74 ITGB3 (0.83) ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105508-B1 Integrin receptors antagonists ABBOTT GMBH & CO. KG (DE) 2006-09-12 US disclosed