Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | TGM2 | P21980 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879640 | 1.00 | MAPT (0.63) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL5879639 | 1.00 | MAPT (0.63) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL30952119 | 0.90 | MAPT (0.77) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL3245039 | 0.90 | MAPT (0.77) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL3245042 | 0.90 | MAPT (0.77) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL9041594 | 0.86 | TGM2 (0.55) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL9041488 | 0.86 | TGM2 (0.55) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL9041602 | 0.86 | TGM2 (0.55) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL9041481 | 0.86 | TGM2 (0.55) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL12143508 | 0.83 | MAPT (0.58) | MAPTALDH1A1NPSR1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |