Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24398108 | 0.74 | TSPO (0.52) | TSPOHDAC8RAB9APDGFRAFER | |
| SCHEMBL9618341 | 0.74 | CA12 (0.65) | CA12CA9APEX1PTGES | |
| SCHEMBL23022773 | 0.74 | PDGFRA (0.52) | TSPOHDAC8RAB9APDGFRAFER | |
| SCHEMBL29744481 | 0.73 | CA12 (1.00) | CA12CA9RAB9A | |
| SCHEMBL522649 | 0.73 | CA12 (1.00) | CA12CA9RAB9A | |
| SCHEMBL31395737 | 0.72 | TSPO (0.53) | TSPOHDAC8RAB9A | |
| SCHEMBL3012558 | 0.72 | CES1 (0.65) | CA12CA9 | |
| Phthalic Acid SCHEMBL30666341 | 0.72 | CA12 (0.82) | CA12CA9APEX1PTGESRAB9A | |
| SCHEMBL30519490 | 0.72 | CES1 (0.65) | CA12CA9 | |
| SCHEMBL9198762 | 0.72 | GAA (0.72) | TSPORAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |