Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 3/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GPR3 | P46089 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273090 | 0.89 | PARP1 (0.57) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL1450262 | 0.89 | PARP1 (0.57) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL7343430 | 0.86 | KDM4E (0.57) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL30273107 | 0.82 | KDM4E (0.59) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL2546622 | 0.82 | KDM4E (0.59) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| Hydrochloric Acid SCHEMBL16858767 | 0.81 | KDM4E (0.58) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| Hydrochloric Acid SCHEMBL2571835 | 0.81 | KDM4E (0.58) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL4178270 | 0.78 | PARP1 (0.57) | PARP1LMNASMN1; SMN2CSNK2A2CSNK2B | |
| SCHEMBL17109319 | 0.77 | PARP1 (0.55) | PARP1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL13558618 | 0.76 | PARP1 (0.53) | PARP1KDM4EALDH1A1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20040077638-A1 | Novel integrin receptor antagonists | BASF AKTIENGESELLCHAFT (DE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077638-A1 | Novel integrin receptor antagonists | ITGB3, ITGAV, ITGA2B | PARP1 2769/4885KDM4E 3784/4885ALDH1A1 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.