Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | HTT | P42858 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879842 | 1.00 | KDM4E (0.55) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5880199 | 0.88 | LMNA (0.47) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5880203 | 0.88 | LMNA (0.47) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5880124 | 0.84 | MAPT (0.58) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5880128 | 0.84 | MAPT (0.58) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5880054 | 0.83 | MAPT (0.54) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5879870 | 0.83 | LMNA (0.57) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL6379352 | 0.83 | LMNA (0.57) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL6374926 | 0.83 | MAPT (0.54) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL5879777 | 0.82 | LMNA (0.51) | KDM4EGAAMAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |