Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SGK1 | O00141 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879886 | 1.00 | LMNA (0.49) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5880013 | 0.90 | MAPT (0.49) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5880009 | 0.90 | MAPT (0.49) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5879821 | 0.89 | CSNK1D (0.42) | LMNAMAPTSGK1ALOX15RXFP1 | |
| SCHEMBL5879826 | 0.89 | CSNK1D (0.42) | LMNAMAPTSGK1ALOX15RXFP1 | |
| SCHEMBL5879622 | 0.88 | LMNA (0.60) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5879620 | 0.88 | LMNA (0.60) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5880160 | 0.85 | LMNA (0.50) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5880164 | 0.85 | LMNA (0.50) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL5879875 | 0.84 | LMNA (0.53) | LMNAMAPTKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |