Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880269 | 1.00 | MAPT (0.45) | MAPTALDH1A1LMNACSNK1DPTGS2 | |
| SCHEMBL5880218 | 0.93 | MAPT (0.46) | MAPTALDH1A1LMNACSNK1DFFAR2 | |
| SCHEMBL5880215 | 0.93 | MAPT (0.46) | MAPTALDH1A1LMNACSNK1DFFAR2 | |
| SCHEMBL5880010 | 0.92 | MAPT (0.45) | MAPTALDH1A1LMNACSNK1DFFAR2 | |
| SCHEMBL5880014 | 0.92 | MAPT (0.45) | MAPTALDH1A1LMNACSNK1DFFAR2 | |
| SCHEMBL5879982 | 0.91 | GRK2 (0.43) | MAPTALDH1A1LMNACSNK1DFFAR2 | |
| SCHEMBL5879985 | 0.91 | GRK2 (0.43) | MAPTALDH1A1LMNACSNK1DFFAR2 | |
| SCHEMBL5879717 | 0.91 | MAPT (0.54) | MAPTALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL5879720 | 0.91 | MAPT (0.54) | MAPTALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL5879719 | 0.89 | ALDH1A1 (0.49) | MAPTALDH1A1LMNACSNK1DFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |