SCHEMBL58803

SCHEMBL58803

Cc1nn(-c2cc(C(=O)O)cc(C(=O)O)c2)c(N=Nc2c(C)nn(-c3nc(O)nc(-n4nc(C)c(N=Nc5c(C#N)c(C)nn5-c5cc(C(=O)O)cc(C(=O)O)c5)c4N)n3)c2N)c1C#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.39
RAB9A P51151 6/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
NPC1 O15118 5/20 0.39
TDP1 Q9NUW8 4/20 0.39
MAPK1 P28482 4/20 0.39
HPGD P15428 2/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.33
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.32
GLA P06280 2/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13762790 0.95 MAPT (0.36) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL12552944 0.93 MAPT (0.38) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL10052073 0.93 NPC1 (0.35) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL4400206 0.92 MAPT (0.38) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL17722451 0.91 MAPT (0.32) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL13159219 0.90 NPC1 (0.33) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL14191463 0.88 GAA (0.32) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL12552946 0.86 NPC1 (0.34) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL58810 0.86 XDH (0.41) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL15233472 0.86 MAPT (0.32) MAPTRAB9ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315686-B2 Water-based ink for ink-jet recording, water-based ink set for ink-jet recording, ink cartridge, and ink-jet recording method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9056997-B2 Ink-jet recording apparatus, ink-jet recording method, recorded matter and composite black BROTHER KOGYO KABUSHIKI KAISHA (JP) 2015-06-16 US disclosed
US-9033483-B2 Water-based ink set for ink-jet recording, water-based ink, and ink-jet recording method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2015-05-19 US disclosed
US-20150116392-A1 Ink-Jet Recording Apparatus, Ink-Jet Recording Method, Recorded Matter and Composite Black BROTHER KOGYO KABUSHIKI KAISHA (JP) 2015-04-30 US disclosed
US-8864297-B2 Water-based ink set for ink-jet recording, ink-jet recording method and ink-jet recording apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2014-10-21 US disclosed
US-20140292901-A1 Water-Based Ink for Ink-Jet Recording, Water-Based Ink Set for Ink-Jet Recording, Ink Cartridge, and Ink-Jet Recording Method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2014-10-02 US disclosed
US-20130182054-A1 Water-Based Ink Set For Ink-Jet Recording, Ink-Jet Recording Method and Ink-Jet Recording Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2013-07-18 US disclosed
US-8460449-B2 Water-based ink set for ink jet recording, ink cartridge, and ink-jet recording apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2013-06-11 US disclosed
US-20130083145-A1 Water-Based Ink Set for Ink-Jet Recording, Water-Based Ink, and Ink-Jet Recording Method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2013-04-04 US disclosed
US-8282719-B2 Water-based ink for ink-jet recording, ink cartridge, ink-jet recording apparatus and method of stabilizing water-based ink for ink-jet recording BROTHER KOGYO KABUSHIKI KAISHA (JP) 2012-10-09 US disclosed
US-20120081453-A1 WATER-BASED INK SET FOR INK-JET RECORDING, INK-JET RECORDING METHOD, AND INK-JET RECORDING APPARATUS BROTHER KOGYO KABUSHIKI KAISHA (JP) 2012-04-05 US disclosed
US-8128747-B2 Water-based ink for ink-jet recording, ink cartridge and ink-jet recording apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
US-8114208-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2012-02-14 US disclosed
US-8083341-B2 Thermal ink-jet ink and ink cartridge using the ink CANON KABUSHIKI KAISHA (JP) 2011-12-27 US disclosed
US-20110128333-A1 Water-Based Ink Set for Ink Jet Recording, Ink Cartridge, and Ink-Jet Recording Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2011-06-02 US disclosed
US-20090274839-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-11-05 US disclosed
US-20090165672-A1 Water-Based Ink for Ink-Jet Recording, Ink Cartridge and Ink-Jet Recording Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2009-07-02 US disclosed
US-7553358-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-30 US disclosed
US-20080274285-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
US-20080151028-A1 THERMAL INK-JET INK AND INK CARTRIDGE USING THE INK CANON KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed