SCHEMBL5880398

SCHEMBL5880398

Cc1ccc(S(=O)(=O)C(N)(CN)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
GAA P10253 2/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TLR9 Q9NR96 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
G6PD P11413 2/20 0.40
F2 P00734 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8213967 0.98 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL10598907 0.79 CA12 (0.44) ALDH1A1CA1CA2CA12CA9
SCHEMBL31420178 0.78 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
Hydrochloric Acid SCHEMBL28375924 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL7812091 0.77 CA1 (0.54) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL7372959 0.77 ALDH1A1 (0.45) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL30565133 0.73 GAA (0.59) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL5031190 0.73 CYP3A4 (0.46) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL8473010 0.73 ALDH1A1 (0.49) ALDH1A1CYP3A4CYP2C9CYP2C19CA1
SCHEMBL10850381 0.73 ALDH1A1 (0.49) ALDH1A1CYP3A4CYP2C9CYP2C19CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060128978-A1 Diepoxide derivatives of N, N*-disubstituted disulfonamides PEWS R G 2006-06-15 US claimed
US-7153925-B2 Condensation polymers from N, N*-disubstituted disulfonamides PEWS R GARTH 2006-12-26 US disclosed
US-20060128924-A1 Novel condensation polymers from N, N*-disubstituted disulfonamides PEWS R G 2006-06-15 US disclosed
US-20060128978-A1 Diepoxide derivatives of N, N*-disubstituted disulfonamides PEWS R G 2006-06-15 US disclosed
US-6022522-A DETECTABLY LABELED BICONJUGATE COMPOUND WHICH COMPRISES A MONOCLONAL ANTIBODY AND A TECHTINIUM-99M COUPLED TO A CHELATING AGENT HAVING A RIGID CYCLIC HYDROCARBON BACKBONE OF GIVEN FORMULA, COUPLED TO THE MONOCLONAL ANTIBODY BROOKHAVEN SCIENCE ASSOCIATES (US) 2000-02-08 US disclosed
US-5783169-A RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 1998-07-21 US disclosed