Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607570 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL891373 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL5878872 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL284791 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL1716734 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL11047324 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL11048015 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL2182533 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL892280 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 | |
| SCHEMBL3161067 | 0.82 | ACLY (0.63) | ACLYACACBACACATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6199641-A | — | — | None | — | — | JP | disclosed |
| US-20220056256-A1 | VISCOUS COMPOSITION | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2022-02-24 | — | — | US | disclosed |
| EP-3932988-A1 | VISCOUS COMPOSITION | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2022-01-05 | — | — | EP | disclosed |
| US-7138365-B2 | Thickener comprising hydroxyalkylated polyhydric alcohol ether compound and high-viscosity liquid detergent composition containing the same | KAWAKEN FINE CHEMICAL CO., LTD. (JP) | 2006-11-21 | — | — | US | disclosed |
| US-20040214739-A1 | Thickener comprising hydroxyalkylated polyhydric alcohol ether compound and high-viscosity liquid detergent composition containing the same | KAWAKEN FINE CHEMICALS, CO., LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1411112-A1 | THICKENER COMPRISING HYDROXYALKYLATED POLYHYDRIC ALCOHOL ETHER COMPOUND AND HIGH−VISCOSITY LIQUID DETERGENT COMPOSITION CONTAINING THE SAME | Kawaken Fine Chemicals Co., Ltd. (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6121470-A | ANIONIC SURFACTANTS, DETERGENTS; STORAGE STABILITY; WASHING SKIN AND HAIR; HYDROLYSIS, SALT EXCHANGING | KAO CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0752983-B1 | NOVEL GLYCINE DERIVATIVES, INTERMEDIATES THEREFOR AND CLEANSER COMPOSITIONS COMPRISING THEM | KAO CORP (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0646641-B1 | Method of stabilizing preparation for contact lenses | SENJU PHARMA CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0752983-A1 | NOVEL GLYCINE DERIVATIVES, INTERMEDIATES THEREFOR AND CLEANSER COMPOSITIONS COMPRISING THEM | Kao Corporation (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026329-A1 | NOVEL GLYCINE DERIVATIVES, INTERMEDIATES THEREFOR AND CLEANSER COMPOSITIONS COMPRISING THEM | KAO CORPORATION (JP) | 1995-10-05 | — | — | WO | disclosed |
| EP-0646641-A2 | Method of stabilizing preparation for contact lenses | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-05 | — | — | EP | disclosed |
| JP-H06199641-A | HAIR DYE | LION CORP | 1994-07-19 | — | — | JP | disclosed |