Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702661 | 0.76 | — | — | |
| SCHEMBL4566706 | 0.74 | — | — | |
| SCHEMBL3976323 | 0.70 | — | — | |
| SCHEMBL28253806 | 0.70 | — | — | |
| SCHEMBL28102667 | 0.68 | IDO1 (0.31) | — | |
| SCHEMBL28285476 | 0.67 | TTK (0.30) | — | |
| SCHEMBL3979369 | 0.67 | — | — | |
| SCHEMBL5881066 | 0.66 | GRIN2B (0.35) | CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL8734773 | 0.65 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL5880902 | 0.64 | SIGMAR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122570-B2 | Tetrahydrocarbazol derivatives as ligands for G-protein-coupled receptors (GPCR) | ZENTARIS AG (DE) | 2006-10-17 | — | — | US | disclosed |