Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961364 | 0.81 | SLC6A2 (0.41) | OGASLC6A4 | |
| SCHEMBL6133472 | 0.81 | SLC6A2 (0.41) | OGASLC6A4 | |
| SCHEMBL8588353 | 0.81 | SLC6A2 (0.41) | OGASLC6A4 | |
| SCHEMBL7849263 | 0.81 | SLC6A2 (0.41) | OGASLC6A4 | |
| SCHEMBL11961363 | 0.81 | SLC6A2 (0.41) | OGASLC6A4 | |
| SCHEMBL31362924 | 0.78 | IDO1 (0.42) | IDO1AGXTSLC6A4APPMAOB | |
| SCHEMBL2610461 | 0.75 | IDO1 (0.57) | IDO1AGXTSLC6A4APPMAOB | |
| SCHEMBL28733900 | 0.75 | FFAR1 (0.39) | IDO1AGXTAPP | |
| SCHEMBL28733903 | 0.75 | FFAR1 (0.39) | IDO1AGXTAPP | |
| SCHEMBL28733902 | 0.75 | FFAR1 (0.39) | IDO1AGXTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989450-B2 | Synthesis of epothilones and related analogs | THE UNIVERSITY OF MISSISSIPPI (US) | 2006-01-24 | — | — | US | disclosed |
| EP-1414384-A4 | SYNTHESIS OF EPOTHILONES AND RELATES ANALOGS | UNIV MISSISSIPPI (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1414384-A2 | SYNTHESIS OF EPOTHILONES AND RELATES ANALOGS | The University of Mississippi (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20020091269-A1 | Synthesis of epothilones and related analogs | TAPESTRY PHARMACEUTICALS, INC. | 2002-07-11 | — | — | US | disclosed |
| WO-2002030356-A2 | SYNTHESIS OF EPOTHILONES AND RELATES ANALOGS | THE UNIVERSITY OF MISSISSIPI (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091269-A1 | Synthesis of epothilones and related analogs | DHPS, SQLE, FDFT1 | IDO1 3778/4885AGXT 723/4885OGA 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.