Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.71 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.71 |
| ▸ | BRD4 | O60885 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5881303 | 0.91 | GRIA1 (0.59) | GRIA1GRIA2BRD4MEN1KMT2A | |
| SCHEMBL5881315 | 0.91 | GRIA2 (0.62) | GRIA1GRIA2BRD4MEN1KMT2A | |
| SCHEMBL4164893 | 0.91 | GRIA1 (0.58) | GRIA1GRIA2MEN1KMT2AKDM4E | |
| SCHEMBL4169852 | 0.91 | GRIA1 (0.58) | GRIA1GRIA2MEN1KMT2AKDM4E | |
| SCHEMBL4164890 | 0.91 | GRIA1 (0.58) | GRIA1GRIA2MEN1KMT2AKDM4E | |
| SCHEMBL8793610 | 0.89 | GRIA1 (0.76) | GRIA1GRIA2BRD4MEN1KMT2A | |
| SCHEMBL6987263 | 0.89 | GRIA1 (0.76) | GRIA1GRIA2BRD4MEN1KMT2A | |
| SCHEMBL4160736 | 0.89 | GRIA2 (0.55) | GRIA1GRIA2BRD4MEN1KMT2A | |
| SCHEMBL4164934 | 0.89 | GRIA2 (0.55) | GRIA1GRIA2BRD4MEN1KMT2A | |
| SCHEMBL4160741 | 0.89 | GRIA2 (0.55) | GRIA1GRIA2BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053082-B1 | 2,3-benzodiazepine derivatives | EGIS GYOGYSZERGYAR RT. (HU) | 2006-05-30 | — | — | US | disclosed |
| EP-1200442-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | EGIS GY GYSZERGY R RT (HU) | 2003-06-25 | — | — | EP | disclosed |