Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.76 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.76 |
| ▸ | BRD4 | O60885 | 5/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793610 | 1.00 | GRIA1 (0.76) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL6615773 | 0.90 | GRIA1 (0.60) | GRIA1GRIA2TERTMEN1KMT2A | |
| SCHEMBL6991386 | 0.90 | GRIA1 (0.60) | GRIA1GRIA2TERTMEN1KMT2A | |
| SCHEMBL5429840 | 0.90 | GRIA1 (0.60) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL5881337 | 0.89 | GRIA1 (0.71) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL7226682 | 0.88 | GRIA1 (0.60) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL5416041 | 0.88 | GRIA1 (0.59) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL5416047 | 0.88 | GRIA1 (0.59) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL5433568 | 0.87 | GRIA1 (0.58) | GRIA1GRIA2BRD4TERTMEN1 | |
| SCHEMBL8793131 | 0.87 | GRIA1 (0.59) | GRIA1GRIA2BRD4TERTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699677-B1 | Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives | LILLY CO ELI (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6160133-A | Synthesis of (S)-α-methyl-1,3-benzodioxole-5-ethanol and derivatives | ELI LILLY AND COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-5986114-A | MUSCLE RELAXANTS, NERVOUS SYSTEM DISORDERS OR ANTICONVULSANTS | ELI LILLY AND COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| US-5665878-A | Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives | ELI LILLY AND COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0699677-A1 | Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives | ELI LILLY AND COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |