Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 4/20 | 0.68 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5881321 | 0.92 | GRIA2 (0.81) | GRIA2GRIA1BRD4MEN1KMT2A | |
| SCHEMBL5881322 | 0.90 | GRIA2 (0.67) | GRIA2GRIA1BRD4MEN1KMT2A | |
| SCHEMBL5881315 | 0.88 | GRIA2 (0.62) | GRIA2GRIA1BRD4MEN1KMT2A | |
| SCHEMBL4170430 | 0.88 | GRIA2 (0.66) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4170440 | 0.88 | GRIA2 (0.66) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4163394 | 0.88 | GRIA2 (0.66) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4168322 | 0.85 | GRIA2 (0.62) | GRIA2GRIA1BRD4MEN1KMT2A | |
| SCHEMBL4168319 | 0.85 | GRIA2 (0.62) | GRIA2GRIA1BRD4MEN1KMT2A | |
| SCHEMBL4177208 | 0.85 | GRIA2 (0.62) | GRIA2GRIA1BRD4MEN1KMT2A | |
| SCHEMBL4156600 | 0.81 | GRIA2 (0.67) | GRIA2GRIA1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053082-B1 | 2,3-benzodiazepine derivatives | EGIS GYOGYSZERGYAR RT. (HU) | 2006-05-30 | — | — | US | claimed |
| EP-1200442-B8 | 2,3-BENZODIAZEPINE DERIVATIVES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-08-20 | — | — | EP | claimed |
| EP-1200442-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | EGIS GY GYSZERGY R RT (HU) | 2003-06-25 | — | — | EP | claimed |
| EP-1200442-A1 | 2,3-BENZODIAZEPINE DERIVATIVES | Egis Gyogyszergyar Rt. (HU) | 2002-05-02 | — | — | EP | claimed |
| WO-2001004122-A2 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | EGIS Gyógyszergyár Rt. (HU) | 2001-01-18 | — | — | WO | claimed |
| US-7053082-B1 | 2,3-benzodiazepine derivatives | EGIS GYOGYSZERGYAR RT. (HU) | 2006-05-30 | — | — | US | disclosed |
| EP-1200442-B8 | 2,3-BENZODIAZEPINE DERIVATIVES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-08-20 | — | — | EP | disclosed |
| EP-1200442-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | EGIS GY GYSZERGY R RT (HU) | 2003-06-25 | — | — | EP | disclosed |
| EP-1200442-A1 | 2,3-BENZODIAZEPINE DERIVATIVES | Egis Gyogyszergyar Rt. (HU) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004122-A2 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | EGIS Gyógyszergyár Rt. (HU) | 2001-01-18 | — | — | WO | disclosed |