Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 3/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156595 | 1.00 | GRIA2 (0.67) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4163394 | 0.93 | GRIA2 (0.66) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4170440 | 0.93 | GRIA2 (0.66) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4170430 | 0.93 | GRIA2 (0.66) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Talampanel SCHEMBL30272868 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Talampanel SCHEMBL118011 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Talampanel SCHEMBL118012 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4164890 | 0.85 | GRIA1 (0.58) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4164893 | 0.85 | GRIA1 (0.58) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL4169852 | 0.85 | GRIA1 (0.58) | GRIA2GRIA1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233913-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2009-09-17 | — | — | US | disclosed |
| EP-1979308-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | EGIS Gyógyszergyár Nyrt (HU) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007077469-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | EGIS GYÓGYSZERGYÁR (HU) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233913-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | GABRA2, GABRA3, GABRB2 | GRIA2 47/4885GRIA1 75/4885MEN1 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.