SCHEMBL5883374

SCHEMBL5883374

CCOc1ccnc(C(=O)O)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.42
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GLA P06280 1/20 0.42
KDM4E B2RXH2 6/20 0.42
ALDH1A1 P00352 3/20 0.42
ALOX15 P16050 3/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 3/20 0.41
IKBKB O14920 1/20 0.40
MAPT P10636 4/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
ASPH Q12797 1/20 0.40
KDM8 Q8N371 1/20 0.40
CYP3A4 P08684 1/20 0.38
BLM P54132 1/20 0.38
AGER Q15109 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19726591 0.86 CYP3A4 (0.43) L3MBTL1HPGDSMN1; SMN2GLAKDM4E
SCHEMBL2243932 0.84 KDM4E (0.41) L3MBTL1KDM4EALDH1A1ALOX15GAA
SCHEMBL753212 0.82 CA12 (0.44) L3MBTL1HPGDKDM4EALDH1A1ALOX15
Hydrochloric Acid SCHEMBL5583653 0.81 CA12 (0.43) L3MBTL1HPGDKDM4EALDH1A1ALOX15
SCHEMBL126180 0.77 MEN1 (0.54) L3MBTL1HPGDGLAKDM4EALDH1A1
SCHEMBL5820837 0.77 KDM4E (0.44) L3MBTL1KDM4EALDH1A1ALOX15GAA
SCHEMBL8883715 0.76 SMN1; SMN2 (0.37) HPGDSMN1; SMN2KDM4EALDH1A1ALOX15
Hydrochloric Acid SCHEMBL17028445 0.76 MEN1 (0.52) L3MBTL1HPGDGLAKDM4EALDH1A1
SCHEMBL2243931 0.75 KDM4E (0.39) L3MBTL1KDM4EALDH1A1ALOX15TSHR
SCHEMBL8882700 0.74 GRIN3B (0.39) L3MBTL1HPGDSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3166611-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-09-16 EP disclosed
EP-3166611-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-09-16 EP disclosed
CN-106573005-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2020-05-29 CN disclosed
CN-106659724-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2020-04-28 CN disclosed
EP-3166927-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-04-22 EP disclosed
EP-3166927-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-04-22 EP disclosed
EP-3166612-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2019-06-12 EP disclosed
EP-3166612-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2019-06-12 EP disclosed
US-9718783-B2 Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids DOW AGROSCIENCES LLC (US) 2017-08-01 US disclosed
US-9718783-B2 Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids DOW AGROSCIENCES LLC (US) 2017-08-01 US disclosed
US-RE39991-E1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation DOW AGROSCIENCES LLC (US) 2008-01-01 US disclosed
US-7034035-B2 Fungicidal mono-, bi-, and tri-cycloheteroalkyl amides and their compositions, methods of use and preparation DOW AGROSCIENCES LLC (US) 2006-04-25 US disclosed
US-6927225-B2 Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation DOW AGROSCIENCES LLC (US) 2005-08-09 US disclosed
US-20040034025-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation RICKS MICHAEL J (US) 2004-02-19 US disclosed
US-6521622-B1 Effective against plant pathogens and wood decaying fungi DOW AGROSCIENCES LLC 2003-02-18 US disclosed
US-20030022903-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation RICKS MICHAEL J (US) 2003-01-30 US disclosed
US-20030022902-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation RICKS MICHAEL J (US) 2003-01-30 US disclosed
US-20030018012-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation RICKS MICHAEL J (US) 2003-01-23 US disclosed
US-20030018052-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation RICKS MICHAEL J (US) 2003-01-23 US disclosed
US-20020177578-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation RICKS MICHAEL J (US) 2002-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018012-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation CYP4X1, CYP1A1, NAT1 L3MBTL1 3933/4885HPGD 1759/4885SMN1; SMN2 4419/4885
US-20020177578-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation CYP4X1, CYP1A1, NAT1 L3MBTL1 3933/4885HPGD 1759/4885SMN1; SMN2 4419/4885
US-20040034025-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation AADAC, NAT1, AHR L3MBTL1 3980/4885HPGD 995/4885SMN1; SMN2 4048/4885
US-20030022903-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation CYP4X1, NAT1, CYP1A1 L3MBTL1 4069/4885HPGD 1690/4885SMN1; SMN2 4537/4885
US-20030018052-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation NAT1, CYP4X1, CYP1A1 L3MBTL1 3904/4885HPGD 1551/4885SMN1; SMN2 4433/4885
US-20030022902-A1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation NAT1, CYP1A1, CYP4X1 L3MBTL1 3906/4885HPGD 1752/4885SMN1; SMN2 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.