SCHEMBL126180

SCHEMBL126180

CCOc1cccnc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HTT P42858 1/20 0.54
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 3/20 0.52
GAA P10253 3/20 0.52
ALOX15 P16050 2/20 0.52
MAPT P10636 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
BLM P54132 1/20 0.52
AGER Q15109 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
GLA P06280 1/20 0.51
CYP1A2 P05177 1/20 0.50
MYC P01106 1/20 0.46
HPGD P15428 2/20 0.44
BRD4 O60885 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17028445 0.98 MEN1 (0.52) MEN1KMT2AHTTALDH1A1KDM4E
Tetrahydrofuran SCHEMBL27433096 0.88 HTT (0.45) MEN1KMT2AHTTALDH1A1KDM4E
SCHEMBL286897 0.86 PTPN1 (0.50) MEN1KMT2AHTTALDH1A1KDM4E
SCHEMBL28432444 0.85 ALDH1A1 (0.56) MEN1KMT2AHTTALDH1A1KDM4E
SCHEMBL8881039 0.85 PTPN1 (0.55) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL2276390 0.85 PTPN1 (0.49) MEN1KMT2AHTTALDH1A1KDM4E
SCHEMBL29852549 0.84 ABCB1 (0.50) ALDH1A1KDM4EALOX15MAPTL3MBTL1
SCHEMBL29941277 0.84 MKNK1 (0.48) MEN1KMT2AHTTALDH1A1KDM4E
SCHEMBL6305012 0.84 MKNK1 (0.48) MEN1KMT2AHTTALDH1A1KDM4E
Alcohol SCHEMBL28974251 0.84 KDM4E (0.50) MEN1KMT2AHTTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-111511731-B Olefin compounds as modulators of the farnesol X receptor 百时美施贵宝公司 2023-05-23 CN claimed
EP-2456763-A1 OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS Novartis AG (CH) 2012-05-30 EP claimed
EP-4729052-A1 SUSTAINED RELEASE DOSAGE FORM FOR LOW SOLUBILITY COMPOUND TETRAHYDROCANNABINOL AND METHODS FOR PREPARING OF THIS SUSTAINED RELEASE DOSAGE FORM Emoviar PharmaCon GmbH (DE) 2026-04-22 EP disclosed
EP-4729049-A1 SUSTAINED RELEASE DOSAGE FORM FOR LOW SOLUBILITY COMPOUND AXITINIB AND METHODS FOR PREPARING OF THIS SUSTAINED RELEASE DOSAGE FORM Emoviar PharmaCon GmbH (DE) 2026-04-22 EP disclosed
US-12599610-B2 Solid dosage formulations of an orexin receptor antagonist MERCK SHARP & DOHME LLC (US) 2026-04-14 US disclosed
EP-3725778-B2 FORMULATIONS OF ENZALUTAMIDE MEDIVATION PROSTATE THERAPEUTICS LLC (US) 2026-01-07 EP disclosed
US-12502357-B2 Formulations of enzalutamide ASTELLAS PHARMA INC. (JP) 2025-12-23 US disclosed
US-12447128-B2 Formulations of enzalutamide ASTELLAS PHARMA INC. (JP) 2025-10-21 US disclosed
US-20250228840-A1 METHODS OF TREATING SJÖGREN-LARSSEN SYNDROME ALDEYRA THERAPEUTICS, INC. 2025-07-17 US disclosed
US-20250221997-A1 TYK2 INHIBITOR FORMULATIONS AND METHODS OF MAKING THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-07-10 US disclosed
US-20010053791-A1 Glycogen phosphorylase inhibitor BEND RESEARCH, INC. 2001-12-20 US disclosed
WO-2001068055-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER PRODUCTS INC. (US) 2001-09-20 WO disclosed
WO-2001068092-A2 GLYCOGEN PHOSPHORYLASE INHIBITOR PFIZER PRODUCTS INC. (US) 2001-09-20 WO disclosed
WO-2001047495-A1 PHARMACEUTICAL COMPOSITIONS PROVIDING ENHANCED DRUG CONCENTRATIONS PFIZER PRODUCTS INC. (US) 2001-07-05 WO disclosed
EP-1027886-A2 Pharmaceutical solid dispersions Pfizer Products Inc. (US) 2000-08-16 EP disclosed
US-5658933-A Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-19 US disclosed
CN-1107144-A Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals HOECHST AG (DE) 1995-08-23 CN disclosed
CN-1107145-A Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals HOECHST AG (DE) 1995-08-23 CN disclosed
US-4764522-A ANTIDEPRESSANT, ANTIPARKINSON DISEASE HOFFMANN-LA ROCHE INC. (US) 1988-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599610-B2 Solid dosage formulations of an orexin receptor antagonist CRH, HCRTR2, HCRTR1 MEN1 3111/4885KMT2A 514/4885HTT 132/4885
US-12502357-B2 Formulations of enzalutamide AR, KLK3, NR5A1 MEN1 1023/4885KMT2A 578/4885HTT 3354/4885
US-20250221997-A1 TYK2 INHIBITOR FORMULATIONS AND METHODS OF MAKING THE SAME TYK2, JAK1, JAK2 MEN1 801/4885KMT2A 166/4885HTT 821/4885
US-20010053791-A1 Glycogen phosphorylase inhibitor PYGL, PYGM, GYS2 MEN1 3048/4885KMT2A 3727/4885HTT 1723/4885
US-20250228840-A1 METHODS OF TREATING SJÖGREN-LARSSEN SYNDROME SSB, HRH2, ASAH2 MEN1 2697/4885KMT2A 2869/4885HTT 1446/4885
US-12447128-B2 Formulations of enzalutamide AR, KLK3, NR5A1 MEN1 1023/4885KMT2A 578/4885HTT 3354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.