SCHEMBL5883808

SCHEMBL5883808

O=[PH](Oc1ccccc1)Oc1ccccc1.[NaH].[NaH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.43
TSHR P16473 1/20 0.43
CA4 P22748 1/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
SRC P12931 1/20 0.37
GSTP1 P09211 1/20 0.37
KCNA3 P22001 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX15 P16050 1/20 0.36
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
NSD2 O96028 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HKDC1 Q2TB90 1/20 0.34
TLR9 Q9NR96 1/20 0.34
MGLL Q99685 1/20 0.34
DAO P14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11350255 1.00 LTA4H (0.43) LTA4HTSHRCA4CA1CA2
SCHEMBL20943 0.97 LTA4H (0.45) LTA4HTSHRCA4CA1CA2
SCHEMBL29790853 0.97 LTA4H (0.45) LTA4HTSHRCA4CA1CA2
Benzene SCHEMBL11134259 0.97 LTA4H (0.45) LTA4HTSHRCA4CA1CA2
SCHEMBL31506397 0.94 LTA4H (0.43) LTA4HTSHRCA4CA1CA2
SCHEMBL13805761 0.94 LTA4H (0.43) LTA4HTSHRCA4CA1CA2
SCHEMBL31674356 0.94 LTA4H (0.43) LTA4HTSHRCA4CA1CA2
SCHEMBL31345228 0.94 LTA4H (0.43) LTA4HTSHRCA4CA1CA2
SCHEMBL31506398 0.94 LTA4H (0.43) LTA4HTSHRCA4CA1CA2
SCHEMBL11350262 0.94 LTA4H (0.43) LTA4HTSHRCA4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39246-E1 Esterification catalysts and processes therefor and therewith E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-08-22 US disclosed
EP-1235647-A1 ESTERIFICATION CATALYST COMPOSITIONS AND USE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-09-04 EP disclosed
WO-2001039885-A1 ESTERIFICATION CATALYST COMPOSITIONS AND USE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-06-07 WO disclosed
US-6166170-A Esterification catalysts and processes therefor and therewith E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-26 US disclosed