SCHEMBL588389

SCHEMBL588389

O=C(O)c1cccc(Br)c1Br

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.53
ALDH1A1 P00352 7/20 0.52
ALOX15 P16050 1/20 0.52
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
FABP4 P15090 1/20 0.47
TSHR P16473 1/20 0.45
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
KMT2A Q03164 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HMGB1 P09429 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA7 P43166 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1116170 0.87 ALDH1A1 (0.60) PRNPALDH1A1ALOX15NR4A1NR4A2
SCHEMBL8495468 0.83 PRNP (0.50) PRNPALDH1A1ALOX15FABP4TSHR
SCHEMBL11226966 0.82 ALDH1A1 (0.48) PRNPALDH1A1ALOX15NR4A1NR4A2
SCHEMBL29875252 0.82 PRNP (0.42) PRNPALDH1A1ALOX15FABP4HPGD
SCHEMBL11816441 0.81 PRNP (0.50) PRNPALDH1A1ALOX15NR4A1NR4A2
SCHEMBL49806 0.80 ALDH1A1 (0.65) PRNPALDH1A1ALOX15FABP4TSHR
SCHEMBL30892252 0.79 ALDH1A1 (0.57) PRNPALDH1A1ALOX15NR4A1NR4A2
SCHEMBL9136350 0.79 PRNP (0.56) PRNPALDH1A1ALOX15FABP4TSHR
SCHEMBL29540504 0.79 PRNP (0.56) PRNPALDH1A1ALOX15NR4A1NR4A2
SCHEMBL28482995 0.79 PRNP (0.39) PRNPALDH1A1ALOX15FABP4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN claimed
CN-110527106-A Multicore multivariable metal-organic framework material and its synthesis, application UNIV FUJIAN 2019-12-03 CN claimed
EP-2935430-B1 FLAME RETARDANT POLYMER COMPOSITIONS BYK USA INC (US) 2019-05-29 EP claimed
US-10227482-B2 Flame retardant polymer compositions BYK USA INC. (US) 2019-03-12 US claimed
CN-105540749-A Rural garbage leachate tower-type treatment device XUZHOU INST TECHNOLOGY 2016-05-04 CN claimed
US-20150322252-A1 FLAME RETARDANT POLYMER COMPOSITIONS POLYAD SERVICES LLC (US) 2015-11-12 US claimed
EP-2935430-A1 FLAME RETARDANT POLYMER COMPOSITIONS Polyad Services LLC (US) 2015-10-28 EP claimed
CN-103008919-B Low-silver halogen-free lead-free solder paste CHENZHOU GOLD ARROW SOLDER CO LTD 2015-05-27 CN claimed
WO-2014099397-A1 FLAME RETARDANT POLYMER COMPOSITIONS POLYAD SERVICES LLC (US) 2014-06-26 WO claimed
CN-103008920-A Leadless rosin core no-clean scaling powder CHENZHOU GOLD ARROW SOLDER CO LTD 2013-04-03 CN claimed
US-6423756-B1 USING CATALYST SYSTEM CROMPTON CORPORATION 2002-07-23 US claimed
WO-2002048229-A2 PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE CROMPTON CORPORATION (US) 2002-06-20 WO claimed
US-6395796-B1 CONDENSATION OF POLYISOCYANATE AND POLYOL USING DELAYED ACTION AMINE CATALYST FORMED BY REACTION OF HALOCARBOXYLIC ACID AND TERTIARY AMINE CROMPTON CORPORATION 2002-05-28 US claimed
US-6387972-B1 MIXTURE CONTAINING TERTIARY AMINE ADJUVANT CROMPTON CORPORATION 2002-05-14 US claimed
CN-1311767-A Glucocorticoid and thyroid hormone receptor ligands for the treatment of metabolic disorders KAROBIO AB (SE) 2001-09-05 CN claimed
CN-1278257-A Process for producing 7-isoindoline-quinolonecarboxylic acid derivative and intermediate thereof, salt of 7-isoindoline-quinolonecarboxylic acid derivative and hydrate thereof, and composition comprising the same as active ingredient TOYAMA CHEMICAL CO LTD (JP) 2000-12-27 CN claimed
CN-1269372-A Process for producing polyurethane foam plastics CK THE WHITAKER CORP (US) 2000-10-11 CN claimed
EP-1018525-A1 Process for preparing polyurethane foam CK WITCO CORPORATION (US) 2000-07-12 EP claimed
CN-1139435-A New ginkgolide derivatives and process for preparing them SUNKYONG IND LTD (KR) 1997-01-01 CN claimed
US-5185471-A Reacting 5-halo-2-nitrobenzotrifluorides with inorganic base to form 1,1*-oxy-Bis(3-trifluoromethyl-4-nitrobenzen using benzoate catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1993-02-09 US claimed