Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884679 | 0.96 | LMNA (0.41) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884301 | 0.92 | SMN1; SMN2 (0.40) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884478 | 0.91 | MEN1 (0.40) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884268 | 0.86 | MEN1 (0.43) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884751 | 0.84 | SMN1; SMN2 (0.41) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884195 | 0.83 | KMT2A (0.41) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884125 | 0.82 | HPGD (0.37) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5883900 | 0.82 | MEN1 (0.42) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884759 | 0.81 | MEN1 (0.43) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884597 | 0.81 | MEN1 (0.41) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |