Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 12/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584574 | 0.82 | RXRA (0.39) | RXRARXRBRXRGGRIA2SLC5A1 | |
| SCHEMBL584573 | 0.82 | RXRA (0.39) | RXRARXRBRXRGGRIA2SLC5A1 | |
| SCHEMBL11899839 | 0.79 | GRIA2 (0.56) | GRIA2TBXA2R | |
| SCHEMBL7896649 | 0.79 | GRIA2 (0.56) | GRIA2 | |
| SCHEMBL11898524 | 0.79 | GRIA2 (0.56) | GRIA2 | |
| SCHEMBL7898941 | 0.79 | GRIA2 (0.56) | GRIA2TBXA2R | |
| SCHEMBL11898474 | 0.79 | RXRA (0.42) | RXRARXRBRXRGGRIA2 | |
| SCHEMBL586031 | 0.77 | GRIA2 (0.63) | GRIA2 | |
| SCHEMBL7898914 | 0.77 | GRIA2 (0.58) | GRIA2 | |
| SCHEMBL586032 | 0.77 | GRIA2 (0.63) | GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417101-A1 | INDANE DERIVATIVES | MSD Oss B.V. (NL) | 2012-02-15 | — | — | EP | disclosed |