Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884418 | 0.94 | SLC6A2 (0.41) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884880 | 0.90 | SMN1; SMN2 (0.42) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884577 | 0.90 | SLC6A2 (0.43) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884089 | 0.89 | SLC6A2 (0.40) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884658 | 0.89 | DRD2 (0.40) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884626 | 0.83 | KMT2A (0.44) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884127 | 0.82 | KCNH2 (0.41) | SLC6A2SLC6A4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5884607 | 0.81 | KMT2A (0.47) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884560 | 0.80 | SLC6A2 (0.46) | SLC6A2SLC6A4DRD4SMN1; SMN2KMT2A | |
| SCHEMBL5884592 | 0.80 | NPC1 (0.35) | SMN1; SMN2MAPK1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |