Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884693 | 0.80 | MEN1 (0.41) | MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL5884838 | 0.80 | MEN1 (0.41) | MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL5884754 | 0.79 | MEN1 (0.41) | MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL8374769 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8549614 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8373486 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL3113016 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8373505 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8315263 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8205008 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | disclosed |
| EP-1187827-A4 | ANTIVIRAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2002-10-24 | — | — | EP | disclosed |
| EP-1187827-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078746-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2000-12-28 | — | — | WO | disclosed |