Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885023 | 0.90 | KCNH2 (0.37) | SMN1; SMN2KCNH2GPR119MAPTBCHE | |
| SCHEMBL5884360 | 0.88 | MAPT (0.36) | KCNH2GPR119SLC2A1MAPTAR | |
| SCHEMBL5884333 | 0.86 | KCNH2 (0.39) | SMN1; SMN2KCNH2GPR119MAPTACHE | |
| SCHEMBL5884689 | 0.86 | KCNH2 (0.39) | SMN1; SMN2KCNH2GPR119MAPTACHE | |
| SCHEMBL5884227 | 0.85 | NR1I2 (0.35) | KCNH2GPR119SLC2A1MAPTAR | |
| SCHEMBL5884628 | 0.85 | GPR119 (0.37) | SMN1; SMN2KCNH2GPR119MAPTACHE | |
| SCHEMBL5884253 | 0.84 | KMT2A (0.40) | SMN1; SMN2KCNH2GPR119MAPTKMT2A | |
| SCHEMBL5883827 | 0.84 | KMT2A (0.40) | SMN1; SMN2KCNH2GPR119MAPTKMT2A | |
| SCHEMBL5884209 | 0.83 | KCNH2 (0.38) | KCNH2GPR119MAPTACHEKMT2A | |
| SCHEMBL5884916 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2GPR119MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |