⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600094 | 0.71 | — | — | |
| SCHEMBL16320079 | 0.70 | — | — | |
| SCHEMBL7237569 | 0.70 | — | — | |
| SCHEMBL5612855 | 0.64 | — | — | |
| SCHEMBL562753 | 0.64 | KDM4E (0.43) | — | |
| SCHEMBL1250482 | 0.64 | — | — | |
| SCHEMBL3066035 | 0.63 | — | — | |
| SCHEMBL3062201 | 0.63 | — | — | |
| SCHEMBL5637103 | 0.62 | — | — | |
| SCHEMBL2395761 | 0.62 | CA12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230217-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | WO | claimed |
| US-5981570-A | INHIBITING BONE LOSS OR BONE RESORPTION, PARTICULARLY OSTEOPOROSIS, CARDIOVASCULAR-RELATED PATHOLOGICAL CONDITIONS, INCLUDING HYPERLIPIDEMIA. | ELI LILLY AND COMPANY (US) | 1999-11-09 | — | — | US | claimed |
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | US | disclosed |
| WO-2023230217-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | WO | disclosed |
| CN-101578277-A | 5-substituted isoindoline compounds | CELGENE CORP (US) | 2009-11-11 | — | — | CN | disclosed |
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | disclosed |
| EP-1187827-A4 | ANTIVIRAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2002-10-24 | — | — | EP | disclosed |
| EP-1187827-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078746-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2000-12-28 | — | — | WO | disclosed |