⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600094 | 0.72 | — | — | |
| SCHEMBL3066035 | 0.72 | — | — | |
| SCHEMBL2465696 | 0.69 | — | — | |
| SCHEMBL3817904 | 0.69 | — | — | |
| SCHEMBL1736653 | 0.69 | — | — | |
| SCHEMBL3062201 | 0.68 | — | — | |
| SCHEMBL4729327 | 0.67 | — | — | |
| SCHEMBL6219603 | 0.66 | — | — | |
| SCHEMBL5898964 | 0.66 | — | — | |
| SCHEMBL4035019 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893069-B2 | Substituted imidazo[2,1-b]thiazole compounds and uses thereof | GRUENENTHAL GMBH (DE) | 2011-02-22 | — | — | US | claimed |
| US-20070027315-A1 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds | GRUENENTHAL GMBH (DE) | 2007-02-01 | — | — | US | claimed |
| CN-115677674-A | Preparation method of heterocyclic compound containing indolone and 3-acyl benzofuran or indole structure | 浙江理工大学 | 2023-02-03 | — | — | CN | disclosed |
| US-10807964-B2 | Benzothiophene-based selective estrogen receptor downregulators | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200079752-A1 | BENZOTHIOPHENE-BASED SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-03-12 | — | — | US | disclosed |
| US-9999217-B2 | Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures | BIOMATRICA, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9845489-B2 | Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures | BIOMATRICA, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160338342-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | EXACT SCIENCES CORPORATION | 2016-11-24 | — | — | US | disclosed |
| US-20130209997-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-7893069-B2 | Substituted imidazo[2,1-b]thiazole compounds and uses thereof | GRUENENTHAL GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| EP-1716128-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2010-03-31 | — | — | EP | disclosed |
| US-7348347-B2 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds | GRUENENTHAL GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-20070027315-A1 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds | GRUENENTHAL GMBH (DE) | 2007-02-01 | — | — | US | disclosed |
| EP-1716128-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE COMPOUNDS | Grünenthal GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005077924-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE COMPOUNDS | Grünenthal GmbH (DE) | 2005-08-25 | — | — | WO | disclosed |