Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885502 | 1.00 | MAPT (0.56) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5884834 | 0.87 | MAPT (0.56) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5884837 | 0.87 | MAPT (0.56) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885717 | 0.86 | MAPT (0.42) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885713 | 0.86 | MAPT (0.42) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885523 | 0.84 | MAPT (0.41) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885516 | 0.84 | MAPT (0.41) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885238 | 0.83 | MAPT (0.54) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885243 | 0.83 | MAPT (0.54) | MAPTPKMMAPK1KMT2AGAA | |
| SCHEMBL5885341 | 0.83 | MAPT (0.66) | MAPTPKMMAPK1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | claimed |
| US-6824570-B2 | CHROMATIC DIRECT DYES OF 2-AZO BENZIMIDAZOLE, BENZOTHIAZOLE OR BENZOXAOZLE DERIVATIVES | L'OREAL S.A. (FR) | 2004-11-30 | — | — | US | claimed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | claimed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | disclosed |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-06-01 | — | — | US | disclosed |
| US-6824570-B2 | CHROMATIC DIRECT DYES OF 2-AZO BENZIMIDAZOLE, BENZOTHIAZOLE OR BENZOXAOZLE DERIVATIVES | L'OREAL S.A. (FR) | 2004-11-30 | — | — | US | disclosed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | MAPT 468/4885PKM 1871/4885MAPK1 1531/4885 |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | MAPT 1195/4885PKM 87/4885MAPK1 1294/4885 |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | MAPT 1195/4885PKM 87/4885MAPK1 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.