TUBB3

Tubulin beta-3 chain · Q13509 · TUBB3 on Sugi Atlas →

134,641 patent compounds predicted against TUBB3, 85,289 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Curacin A Curacin A (SCHEMBL61304) 1.00 20/20
Vintriptol Vintriptol (SCHEMBL93959) 1.00 15/20
Vindesine Vindesine (SCHEMBL4420) 0.85 13/20
Vindesine Vindesine (SCHEMBL4421) 0.85 13/20
Vindesine Vindesine (SCHEMBL4285) 0.85 12/20
SCHEMBL147173 SCHEMBL147173 0.50 12/20
SCHEMBL147174 SCHEMBL147174 0.50 12/20
Combretastatin Combretastatin (SCHEMBL19955) 1.00 9/20
Combretastatin Combretastatin (SCHEMBL19956) 1.00 9/20
SCHEMBL118593 SCHEMBL118593 0.69 9/20
Centaureidin Centaureidin (SCHEMBL9953) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43160) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43161) 1.00 8/20
SCHEMBL68067 SCHEMBL68067 0.62 8/20
Fosbretabulin Fosbretabulin (SCHEMBL66079) 0.61 8/20
Vinorelbine Vinorelbine (SCHEMBL4765) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18945) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18946) 1.00 7/20
Levofloxacin Anhydrous Levofloxacin Anhydrous (SCHEMBL15397) 0.98 7/20
Ofloxacin Ofloxacin (SCHEMBL24373) 0.98 7/20

Clinical trials — most relevant to TUBB3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparative and Efficacy Study of ACTHar Gel Alone or in Combination With Tacrolimus in Fibrillary Glomerulopathy PHASE4WITHDRAWN
Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer PHASE3COMPLETED
Eribulin Mesylate or Paclitaxel as First- or Second-Line Therapy in Treating Patients With Recurrent Stage IIIC-IV Breast Cancer PHASE3SUSPENDED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy PHASE3UNKNOWN
The ECLA PHRI COLCOVID Trial. Effects of Colchicine on Moderate/High-risk Hospitalized COVID-19 Patients. PHASE3COMPLETED
First-line Gemcitabine Plus Cisplatin in Locally Advanced (IIIC Stage) Breast Cancer Patients PHASE2ACTIVE_NOT_RECRUITING
Vit D and Peripheral Neuropathy in Taxane Naive Patients PHASE2UNKNOWN
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer PHASE2COMPLETED
Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations PHASE2COMPLETED
Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer PHASE1/PHASE2NOT_YET_RECRUITING
Therapy With Docetaxel and ZD1839 for Patients Who Have Advanced Breast Cancer PHASE2COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Exploratory Evaluation of [11C]MPC6827 EARLY_PHASE1COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting nanUNKNOWN
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Importance of the Microtubule Cytoskeleton in Oocyte Competence nanCOMPLETED
Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Single and Combined Approaches nanRECRUITING
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
The Relation of Microtubule-Associated Protein 2 and Cell Migration nanUNKNOWN
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TUBB3 binder may also engage these)

ProteinNameSimilarity
TUBB2B Tubulin beta-2B chain 1.000 landscape →
Q6B856 1.000 Q6B856 →
P85108 1.000 P85108 →
TUBB2A Tubulin beta-2A chain 1.000 landscape →
P46265 1.000 P46265 →
Q27U48 1.000 Q27U48 →
Q2HJ81 1.000 Q2HJ81 →
P68372 1.000 P68372 →
P69893 1.000 P69893 →
Q6GLE7 1.000 Q6GLE7 →
Q3MHM5 1.000 Q3MHM5 →
O44388 1.000 O44388 →
P11833 1.000 P11833 →
Q4R4X8 1.000 Q4R4X8 →
O59837 1.000 O59837 →
P12456 1.000 P12456 →
Q60HC2 1.000 Q60HC2 →
Q2T9S0 1.000 Q2T9S0 →
P61858 1.000 P61858 →
P14140 1.000 P14140 →
P33127 1.000 P33127 →
P09652 1.000 P09652 →
Q9NFZ7 1.000 Q9NFZ7 →
Q24560 1.000 Q24560 →
Q94571 1.000 Q94571 →
P09203 1.000 P09203 →
P32882 1.000 P32882 →
Q875L2 1.000 Q875L2 →
P09244 1.000 P09244 →
Q2KJD0 1.000 Q2KJD0 →