Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626788 | 0.82 | CA12 (0.46) | KDM4ECYP3A4CYP1A2CYP2C9TSHR | |
| SCHEMBL6411967 | 0.74 | TSHR (0.66) | MAPTPOLBGAACYP3A4CYP1A2 | |
| SCHEMBL28026107 | 0.72 | MAPT (0.50) | MAPTKMT2AMEN1GAACYP3A4 | |
| SCHEMBL3391383 | 0.70 | HSP90AA1 (0.46) | KDM4ETSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL7378524 | 0.70 | KDM4E (0.73) | KDM4EMAPTPOLBKMT2AGAA | |
| SCHEMBL7302208 | 0.69 | CA1 (0.52) | KDM4EMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL6380548 | 0.69 | KDM4E (0.46) | KDM4EMAPTPOLBKMT2AMEN1 | |
| SCHEMBL1096209 | 0.69 | KDM4E (0.46) | KDM4EMAPTPOLBKMT2AGAA | |
| SCHEMBL5190252 | 0.69 | CYP3A4 (0.39) | KDM4EMAPTKMT2AGAACYP3A4 | |
| SCHEMBL4628908 | 0.68 | ALDH1A1 (0.47) | KDM4EMAPTCYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942590-A | A kind of preparation method of Nitidine Chloride | 云南民族大学 | 2019-06-28 | — | — | CN | claimed |
| US-4785010-A | AGING RESISTANCE OF HUMANS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | claimed |
| CN-109942590-A | A kind of preparation method of Nitidine Chloride | 云南民族大学 | 2019-06-28 | — | — | CN | disclosed |
| CN-109942590-A | A kind of preparation method of Nitidine Chloride | 云南民族大学 | 2019-06-28 | — | — | CN | disclosed |
| US-7115617-B2 | Amino-substituted pyrimidinyl derivatives and methods of use | AMGEN INC. (US) | 2006-10-03 | — | — | US | disclosed |
| US-4785010-A | AGING RESISTANCE OF HUMANS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | disclosed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | disclosed |