Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MPI | P34949 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RRM1 | P23921 | 1/20 | 0.58 |
| ▸ | RRM2 | P31350 | 1/20 | 0.58 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885538 | 1.00 | GAA (0.70) | GAAKDM4EL3MBTL1MAOBMAPT | |
| SCHEMBL3084339 | 0.89 | GAA (0.79) | GAAKDM4EL3MBTL1MAOBMAPT | |
| SCHEMBL3084344 | 0.89 | GAA (0.79) | GAAKDM4EL3MBTL1MAOBMAPT | |
| Salicylaldehyde Thiosemicarbazone SCHEMBL3072985 | 0.82 | GAA (1.00) | GAAKDM4EL3MBTL1MAOBMAPT | |
| SCHEMBL21519509 | 0.82 | GAA (0.47) | GAAKDM4EL3MBTL1MAOBMAPT | |
| Salicylaldehyde Thiosemicarbazone SCHEMBL29456536 | 0.82 | GAA (1.00) | GAAKDM4EL3MBTL1MAOBMAPT | |
| Salicylaldehyde Thiosemicarbazone SCHEMBL3072988 | 0.82 | GAA (1.00) | GAAKDM4EL3MBTL1MAOBMAPT | |
| SCHEMBL3691048 | 0.81 | KDM4E (0.68) | GAAKDM4EL3MBTL1MAOBMAPT | |
| SCHEMBL3691050 | 0.81 | KDM4E (0.68) | GAAKDM4EL3MBTL1MAOBMAPT | |
| SCHEMBL7650941 | 0.81 | MAOB (1.00) | GAAKDM4EL3MBTL1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041994-B2 | Radioprotective materials and utilization thereof | ALLMIGHTY CO., LTD. (JP) | 2006-05-09 | — | — | US | claimed |
| US-20030080303-A1 | Radioprotective materials and utilization thereof | ALLMIGHTY CO., LTD. (JP) | 2003-05-01 | — | — | US | claimed |