Salicylaldehyde Thiosemicarbazone

Salicylaldehyde Thiosemicarbazone

SCHEMBL3072985

NC(=S)N/N=C/c1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 1.00
KDM4E B2RXH2 5/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
MAPT P10636 3/20 0.76
LMNA P02545 1/20 0.76
MPI P34949 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
MAOB P27338 1/20 0.68
CTRC Q99895 1/20 0.64
DUSP3 P51452 1/20 0.64
PTPN5 P54829 1/20 0.64
PTPN11 Q06124 1/20 0.64
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALDH1A1 P00352 2/20 0.59
CYP3A4 P08684 2/20 0.57
TP53 P04637 1/20 0.57
CYP2D6 P10635 1/20 0.57
HPGD P15428 1/20 0.57
MAPK1 P28482 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylaldehyde Thiosemicarbazone SCHEMBL3072988 1.00 GAA (1.00) GAAKDM4EL3MBTL1MAPTLMNA
Salicylaldehyde Thiosemicarbazone SCHEMBL29456536 1.00 GAA (1.00) GAAKDM4EL3MBTL1MAPTLMNA
Salicylaldehyde Thiosemicarbazone SCHEMBL28467944 0.98 GAA (0.97) GAAKDM4EL3MBTL1MAPTLMNA
Salicylaldehyde Thiosemicarbazone SCHEMBL23145003 0.97 KDM4E (0.93) GAAKDM4EL3MBTL1MAPTLMNA
Salicylaldehyde Thiosemicarbazone SCHEMBL23145004 0.94 KDM4E (0.88) GAAKDM4EL3MBTL1MAPTLMNA
SCHEMBL3084339 0.89 GAA (0.79) GAAKDM4EL3MBTL1MAPTLMNA
SCHEMBL3084344 0.89 GAA (0.79) GAAKDM4EL3MBTL1MAPTLMNA
SCHEMBL18746290 0.86 L3MBTL1 (1.00) GAAKDM4EL3MBTL1MAPTLMNA
SCHEMBL15457449 0.85 L3MBTL1 (0.74) GAAKDM4EL3MBTL1MAPTLMNA
SCHEMBL31084616 0.83 KDM4E (0.71) GAAKDM4EL3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US claimed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US claimed
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 US claimed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP claimed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US claimed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 EP claimed
US-20240167121-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-05-23 US claimed
US-11859263-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-01-02 US claimed
WO-2022245731-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2022-11-24 WO claimed
CN-107532229-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2021-10-08 CN claimed
CN-109824918-B Nano-cellulose-salicylaldehyde thiosemicarbazone-polyvinyl alcohol hydrogel fluorescent probe and preparation method and application thereof 南京林业大学 2021-06-01 CN claimed
US-10961604-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-30 US claimed
US-10954583-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-23 US claimed
CN-107601956-B Supermolecule anti-crack concrete additive and preparation method thereof 迈嘉尔(武汉)高新技术发展有限公司 2021-01-19 CN claimed
CN-111607984-A Antibacterial and antivirus dye slurry and preparation method and application thereof 同曦集团有限公司 2020-09-01 CN claimed
US-20200181737-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-06-11 US claimed
US-20200149131-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-05-14 US claimed
US-20200048736-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC 2020-02-13 US claimed
CN-110713814-A Epoxy resin adhesive and preparation method and application thereof 欧菲影像技术(广州)有限公司 2020-01-21 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 GAA 3949/4885KDM4E 2815/4885L3MBTL1 2693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.