SCHEMBL5886098

SCHEMBL5886098

CC(Cl)OC(=O)N(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9468778 0.81
SCHEMBL10822350 0.79
SCHEMBL306131 0.77 BCHE (0.31)
SCHEMBL10837828 0.77 TSHR (0.31)
SCHEMBL3822564 0.73 MAPT (0.33)
SCHEMBL5131740 0.73 TSHR (0.33)
SCHEMBL9833152 0.73 KMT2A (0.42)
SCHEMBL9220989 0.73
SCHEMBL609519 0.71 TSHR (0.38)
SCHEMBL1126983 0.71 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9770514-B2 Tamper-resistant pharmaceutical dosage forms ExxPharma Therapeutics LLC (US) 2017-09-26 US claimed
US-20150064250-A1 Tamper-Resistant Pharmaceutical Dosage Forms ExxPharma Therapeutics LLC (US) 2015-03-05 US claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-10010620-B2 Tamper-resistant pharmaceutical dosage forms and process for making same ExxPharma Therapeutics LLC (US) 2018-07-03 US disclosed
US-9770514-B2 Tamper-resistant pharmaceutical dosage forms ExxPharma Therapeutics LLC (US) 2017-09-26 US disclosed
US-20160175454-A1 Tamper-Resistant Pharmaceutical Dosage Forms and Process for Making Same NEUROCRINE BIOSCIENCES, INC. 2016-06-23 US disclosed
WO-2015034846-A1 TAMPER-RESISTANT PHARMACEUTICAL DOSAGE FORMS AND PROCESS FOR MAKING SAME ExxPharma Therapeutics LLC (US) 2015-03-12 WO disclosed
US-20150064251-A1 Tamper Resistant Dosage Form Composition And Process Of Making The Same ExxPharma Therapeutics LLC 2015-03-05 US disclosed
US-20150064250-A1 Tamper-Resistant Pharmaceutical Dosage Forms ExxPharma Therapeutics LLC (US) 2015-03-05 US disclosed
US-7122198-B1 Fast dissolving composition with prolonged sweet taste PANACEA BIOTEC LIMITED (IN) 2006-10-17 US disclosed
US-7026360-B1 Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients INPHARMA S.A. (CH) 2006-04-11 US disclosed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP disclosed
US-6121218-A CONTAINS ALCOHOL; ETHER; ORGANIC ACID, POLY ACID, ACID ANHYDRIDE, OR ACID HALIDE; UREA, THIOUREA OR DERIVATIVE THEREOF THOMPSON ANDREW MICHAEL (US) 2000-09-19 US disclosed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO disclosed