Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17092988 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL8909949 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL7737226 | 0.80 | CA14 (0.36) | — | |
| SCHEMBL15254197 | 0.78 | — | — | |
| SCHEMBL9728294 | 0.77 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNAMMP1 | |
| SCHEMBL7852900 | 0.77 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL6893989 | 0.77 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL16965605 | 0.77 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL6893830 | 0.77 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL16965789 | 0.77 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | VERNALIS (R&D) LTD (GB) | 2024-05-09 | — | — | US | disclosed |
| EP-4277892-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2023-11-22 | — | — | EP | disclosed |
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| WO-2022152705-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2022-07-21 | — | — | WO | disclosed |
| CN-107148423-B | Thionucleoside derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2021-07-30 | — | — | CN | disclosed |
| EP-3214090-B1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORP (JP) | 2020-08-19 | — | — | EP | disclosed |
| EP-3405471-B1 | NEW AMMONIUM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2019-10-30 | — | — | EP | disclosed |
| US-10457689-B2 | Ammonium derivatives, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2019-10-29 | — | — | US | disclosed |
| US-10385089-B2 | Thionucleoside derivative or salt thereof, and pharmaceutical composition | FUJIFILM CORPORATION (JP) | 2019-08-20 | — | — | US | disclosed |
| US-20190031677-A1 | AMMONIUM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | VERNALIS (R&D) LTD (GB) | 2019-01-31 | — | — | US | disclosed |
| CN-108602841-A | New ammonium derivative, their preparation method and the pharmaceutical composition containing them | 法国施维雅药厂 | 2018-09-28 | — | — | CN | disclosed |
| US-10059734-B2 | Thionucleoside derivative or salt thereof, and pharmaceutical composition | FUJIFILM CORPORATION (JP) | 2018-08-28 | — | — | US | disclosed |
| CN-107148423-A | Thionucleoside derivatives or its salt and medical composition | 富士胶片株式会社 | 2017-09-08 | — | — | CN | disclosed |
| EP-3214090-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | Fujifilm Corporation (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-20170233429-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2017-08-17 | — | — | US | disclosed |
| WO-2017125224-A1 | NEW AMMONIUM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2017-07-27 | — | — | WO | disclosed |
| EP-0200692-B1 | ANDROSTANE-17-BETA-CARBOXYLIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUND CONTAINING THEM | Aktiebolaget Draco (SE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0104984-B1 | VINYLCARBAMIC ACID ESTERS AND THEIR PREPARATION | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-05-16 | — | — | EP | disclosed |
| US-4804656-A | ANTIINFLAMMATORY AGENTS | AKTIEBOLAGET DRACO (SE) | 1989-02-14 | — | — | US | disclosed |
| EP-0200692-A1 | Androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them | Aktiebolaget Draco (SE) | 1986-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BAX, BCL2A1 | KMT2A 4768/4885MEN1 2444/4885ALDH1A1 1439/4885 |
| US-10385089-B2 | Thionucleoside derivative or salt thereof, and pharmaceutical composition | SLC11A2, RNASE1, KRAS | KMT2A 2290/4885MEN1 2626/4885ALDH1A1 2541/4885 |
| US-10059734-B2 | Thionucleoside derivative or salt thereof, and pharmaceutical composition | SLC11A2, RNASE1, TYMP | KMT2A 2643/4885MEN1 2253/4885ALDH1A1 1881/4885 |
| US-10457689-B2 | Ammonium derivatives, a process for their preparation and pharmaceutical compositions containing them | ARG1, ASS1, ATP6V1B1 | KMT2A 2252/4885MEN1 1107/4885ALDH1A1 1905/4885 |
| US-20190031677-A1 | AMMONIUM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ARG1, ASS1, ATP6V1B1 | KMT2A 2252/4885MEN1 1107/4885ALDH1A1 1905/4885 |
| US-20170233429-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | SLC11A2, RNASE1, TYMP | KMT2A 2643/4885MEN1 2253/4885ALDH1A1 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.