Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886440 | 0.86 | TTBK1 (0.31) | TTBK1CHUK | |
| SCHEMBL5886477 | 0.84 | — | — | |
| SCHEMBL5886369 | 0.82 | KCNH2 (0.32) | — | |
| SCHEMBL5886261 | 0.82 | BRD4 (0.34) | — | |
| SCHEMBL5886442 | 0.81 | KCNH2 (0.36) | — | |
| SCHEMBL4163017 | 0.80 | KCNH2 (0.36) | — | |
| SCHEMBL4155476 | 0.80 | ALOX5AP (0.32) | — | |
| SCHEMBL5886360 | 0.80 | GRM5 (0.32) | — | |
| SCHEMBL4160273 | 0.79 | TGFBR1 (0.33) | — | |
| SCHEMBL5886357 | 0.79 | BRD4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122546-B2 | Imidazol-1-ylmethyl pyridazine derivatives | NEUROGEN CORPORATION (US) | 2006-10-17 | — | — | US | claimed |
| US-7122546-B2 | Imidazol-1-ylmethyl pyridazine derivatives | NEUROGEN CORPORATION (US) | 2006-10-17 | — | — | US | disclosed |