SCHEMBL5886570

SCHEMBL5886570

CCC[C@H]1CC[C@H]([C@H]2CC[C@H](c3cccc(C#N)c3F)CC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 6/20 0.45
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
GRM2 Q14416 2/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
DRD4 P21917 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886557 1.00 OPRL1 (0.45) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL5886564 1.00 OPRL1 (0.45) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9447123 0.91 OPRL1 (0.38) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9447128 0.91 OPRL1 (0.38) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9447160 0.87 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9447157 0.87 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9625380 0.87 OPRL1 (0.46) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL10911944 0.87 OPRL1 (0.46) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9625387 0.87 OPRL1 (0.46) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9625384 0.87 OPRL1 (0.46) OPRL1CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP claimed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP claimed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP claimed
US-7112355-B2 Active matrix type liquid crystal display apparatus HITACHI LTD. (JP) 2006-09-26 US disclosed
US-20050084623-A1 Active matrix type liquid crystal display apparatus IPS ALPHA SUPPORT CO., LTD. (JP) 2005-04-21 US disclosed
US-6849309-B2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 2005-02-01 US disclosed
US-6830787-B1 Active matrix liquid crystal display apparatus HITACHI, LTD. (JP) 2004-12-14 US disclosed
US-20030201422-A1 Active matrix type liquid crystal display apparatus HITACHI DISPLAYS, LTD. (JP) 2003-10-30 US disclosed
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP disclosed
EP-0667555-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2002-08-28 EP disclosed
US-20020039162-A1 ACTIVE MATRIX TYPE LIQUID CRYSTAL DISPLAY APPARATUS OHE MASAHITO (JP) 2002-04-04 US disclosed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP disclosed
US-6011606-A Parallel field active matrix type liquid crystal display using liquid crystal having particular electrical properties HITACHI, LTD. (JP) 2000-01-04 US disclosed
US-5910271-A Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1999-06-08 US disclosed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP disclosed
EP-0667555-A1 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-08-16 EP disclosed