Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | F7 | P08709 | 3/20 | 0.49 |
| ▸ | F3 | P13726 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16417145 | 1.00 | MAPT (0.58) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL653863 | 0.91 | MAPT (0.63) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL15592925 | 0.90 | MAPT (0.56) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL5374521 | 0.88 | MAPT (0.60) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL3742738 | 0.88 | MAPT (0.60) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL3742740 | 0.88 | MAPT (0.60) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL3407185 | 0.87 | ALDH1A1 (0.71) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL3407181 | 0.87 | ALDH1A1 (0.71) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL22451075 | 0.87 | ALDH1A1 (0.71) | MAPTCNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL3408523 | 0.87 | ALDH1A1 (0.71) | MAPTCNR1CNR2ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377056-B1 | STABLE ANALOGS OF CYP450 LIPID METABOLITES AND INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | MASSACHUSETTS EYE & EAR INFIRMARY (US) | 2020-09-23 | — | — | EP | disclosed |
| US-7091369-B2 | Synthesis of polyconjugated fatty acids | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2006-08-15 | — | — | US | disclosed |
| US-20050014826-A1 | Synthesis of polyconjugated fatty acids | THE BOARD OF TRUSTEES OPERATING MICHIGAN STATUE UNIVERSITY (US) | 2005-01-20 | — | — | US | disclosed |