Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17107839 | 0.98 | KDM4E (0.44) | ALDH1A1KDM4EMAPTNSD2MEN1 | |
| Hydrochloric Acid SCHEMBL27089989 | 0.98 | KDM4E (0.44) | ALDH1A1KDM4EMAPTNSD2MEN1 | |
| SCHEMBL7572894 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTNSD2MEN1 | |
| SCHEMBL27964997 | 0.81 | MAPT (0.46) | ALDH1A1KDM4EMAPTNSD2MEN1 | |
| SCHEMBL12163 | 0.80 | KIT (0.41) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL13106176 | 0.77 | KIT (0.44) | KDM4EMEN1KMT2AKDRKIT | |
| SCHEMBL26515852 | 0.77 | PRNP (0.43) | KDRKITPDGFRABTKCHRM4 | |
| SCHEMBL13106271 | 0.77 | POLB (0.46) | KDM4EMAPTKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL2144329 | 0.77 | PDGFRA (0.44) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL16574034 | 0.74 | KIT (0.38) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751353-A | 2, 3-Dimethyl-2H-indazole-6-amine and preparation method thereof | 滁州市庆云医药有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-117924177-A | Preparation method of pazopanib intermediate 2, 3-dimethyl-6-amino-2H-indazole and analogues thereof | 南京杰运医药科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-114380748-B | Synthesis method of 2, 3-dimethyl-6 amino-2H-indazole hydrochloride | 南京杰运医药科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116987066-A | Pyrimidine compound and preparation method and application thereof | 四川大学 | 2023-11-03 | — | — | CN | claimed |
| CN-109212042-B | Analysis method for determining toxicity impurities of pezopyr hydrochloride gene by adopting liquid chromatography-mass spectrometry | 齐鲁制药有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-108299304-A | A method of preparing 2,3- dimethyl -2H- indazole -6- amine hydrochlorates | 中国药科大学 | 2018-07-20 | — | — | CN | claimed |
| CN-103739550-B | 2,3-dimethyl-6-urea-2H-indazole compounds and its preparation method and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-103450085-B | A kind of preparation method of pazopanib hydrochloride key intermediate | ASYMCHEM MEDICAL GROUP (TIANJIN) INC. (CN) | 2015-11-18 | — | — | CN | claimed |
| CN-103739550-A | 2, 3-dimethyl-6-urea-2H-indazole compound and preparation method and application thereof | UNIV CHINA PHARMA | 2014-04-23 | — | — | CN | claimed |
| CN-103450085-A | Preparation method of pazopanib hydrochloride key intermediate | ASYMCHEM LAB TIANJIN CO LTD | 2013-12-18 | — | — | CN | claimed |
| EP-2490536-A1 | COMPOSITIONS AND PROCESSES | Glaxo Wellcome Manufacturing Pte Ltd (SG) | 2012-08-29 | — | — | EP | claimed |
| US-20120197019-A1 | COMPOSITIONS AND PROCESSES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-08-02 | — | — | US | claimed |
| WO-2011050159-A1 | COMPOSITIONS AND PROCESSES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2011-04-28 | — | — | WO | claimed |
| US-20070292513-A1 | CHEMICAL COMPOUNDS | NOVARTIS AG (CH) | 2007-12-20 | — | — | US | claimed |
| CN-120294252-A | 2, 3-Dimethyl-6-amino-2H-indazole solution concentration detection device and detection method thereof | 南京一苇医药科技有限公司 | 2025-07-11 | — | — | CN | disclosed |
| CN-120294252-A | 2, 3-Dimethyl-6-amino-2H-indazole solution concentration detection device and detection method thereof | 南京一苇医药科技有限公司 | 2025-07-11 | — | — | CN | disclosed |
| CN-119751353-A | 2, 3-Dimethyl-2H-indazole-6-amine and preparation method thereof | 滁州市庆云医药有限公司 | 2025-04-04 | — | — | CN | disclosed |
| EP-1515955-A2 | CHEMICAL PROCESS | SmithKline Beecham Corporation (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20040242578-A1 | Pyrimidineamines as angiogenesis modulators | NOVARTIS AG (CH) | 2004-12-02 | — | — | US | disclosed |
| WO-2003106416-A2 | CHEMICAL PROCESS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197019-A1 | COMPOSITIONS AND PROCESSES | PIK3CA, PNP, PIK3CB | ALDH1A1 1956/4885KDM4E 1943/4885MAPT 3565/4885 |
| US-20040242578-A1 | Pyrimidineamines as angiogenesis modulators | TYMS, TYMP, DPYD | ALDH1A1 1108/4885KDM4E 1408/4885MAPT 3924/4885 |
| US-20070292513-A1 | CHEMICAL COMPOUNDS | KDR, FLT4, FLT1 | ALDH1A1 945/4885KDM4E 1688/4885MAPT 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.