Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754908 | 0.92 | SLC18A3 (0.46) | HTTLMNAKMT2ATDP1CYP11B2 | |
| SCHEMBL11588397 | 0.90 | ESR2 (0.55) | ESR2 | |
| SCHEMBL1093487 | 0.87 | ESR2 (0.44) | ESR2HRH3 | |
| SCHEMBL944630 | 0.86 | HTT (0.43) | HTTLMNAHDAC8HDAC6HDAC1 | |
| SCHEMBL18017090 | 0.85 | NOTUM (0.41) | HTTLMNAHDAC8HDAC6HDAC1 | |
| SCHEMBL28584923 | 0.84 | HDAC8 (0.52) | HTTLMNAHDAC8HDAC6HDAC1 | |
| SCHEMBL6275125 | 0.84 | HDAC8 (0.52) | HTTLMNAHDAC8HDAC6HDAC1 | |
| SCHEMBL15260520 | 0.84 | HDAC8 (0.52) | HTTLMNAHDAC8HDAC6HDAC1 | |
| SCHEMBL42782 | 0.84 | HDAC8 (0.52) | HTTLMNAHDAC8HDAC6HDAC1 | |
| SCHEMBL10011868 | 0.84 | HTT (0.42) | HTTLMNAHDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591207-B | Synthesis method of cycloalkyl aryl thioether compound | 台州学院 | 2024-03-26 | — | — | CN | disclosed |
| US-20230161255-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| US-7112697-B1 | Methods for formation of aryl-sulfur and aryl-selenium compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2006-09-26 | — | — | US | disclosed |