SCHEMBL5887762

SCHEMBL5887762

COc1ccc([Se]c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.59
LTA4H P09960 2/20 0.56
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
TRPA1 O75762 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
ALDH1A1 P00352 2/20 0.46
OPRM1 P35372 1/20 0.46
OPRL1 P41146 1/20 0.46
KMT2A Q03164 1/20 0.44
ACHE P22303 1/20 0.44
CYP1A2 P05177 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP2A6 P11509 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681950 0.90 CA1 (0.65) CA4LTA4HCA1CA2CA7
SCHEMBL6676066 0.86 CA4 (0.59) CA4LTA4HCA1CA2CA7
Anisole SCHEMBL28681552 0.83 CA4 (0.56) CA4LTA4HCA1CA2CA7
Anisole SCHEMBL28693340 0.83 CA4 (0.56) CA4LTA4HCA1CA2CA7
SCHEMBL28676687 0.79 RAB9A (0.53) CA1CA2CA7CA9CA12
SCHEMBL6515705 0.77 CA1 (0.77) CA1CA2CES2CES1ALDH1A1
Anisole SCHEMBL10721106 0.76 CA4 (1.00) CA4LTA4HCA1CA2CA7
Anisole SCHEMBL8472521 0.76 CA4 (1.00) CA4LTA4HCA1CA2CA7
Anisole SCHEMBL20328417 0.76
Anisole SCHEMBL30601749 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419094-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS Edison Oncology (US) 2024-08-28 EP disclosed
CN-114805156-B Method for preparing asymmetric aryl seleno ether compound by copper catalysis under room temperature and water phase conditions 浙江工业大学 2024-03-26 CN disclosed
WO-2023069727-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS EDISON ONCOLOGY (US) 2023-04-27 WO disclosed
CN-114805156-A Method for preparing asymmetric arylseleno ether compound under room temperature and water phase conditions by copper catalysis 浙江工业大学 2022-07-29 CN disclosed
CN-113930790-A Synthetic method of aryl selenide compound 南昌大学 2022-01-14 CN disclosed
US-7112697-B1 Methods for formation of aryl-sulfur and aryl-selenium compounds using copper(I) catalysts UNIVERSITY OF MASSACHUSETTS (US) 2006-09-26 US disclosed