Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887996 | 1.00 | PPARG (0.49) | PPARGEPHX2KMT2APPARAGRIK1 | |
| SCHEMBL8815832 | 0.85 | CYP1A2 (0.63) | GRIK1GRIK2CYP1A2MME | |
| SCHEMBL4663230 | 0.81 | CYP1A2 (0.65) | PPARGEPHX2KMT2APPARACYP1A2 | |
| SCHEMBL17497191 | 0.81 | PPARG (0.48) | PPARGEPHX2KMT2APPARAGRIK1 | |
| SCHEMBL8301284 | 0.81 | PPARG (0.48) | PPARGEPHX2KMT2APPARAGRIK1 | |
| SCHEMBL7713444 | 0.78 | PPARG (0.71) | PPARGEPHX2KMT2APPARACYP1A2 | |
| SCHEMBL7713441 | 0.78 | PPARG (0.71) | PPARGEPHX2KMT2APPARACYP1A2 | |
| Hydrochloric Acid SCHEMBL9239573 | 0.77 | PPARG (0.69) | PPARGEPHX2KMT2APPARACYP1A2 | |
| SCHEMBL7325309 | 0.75 | PPARG (0.49) | PPARGEPHX2KMT2APPARACYP1A2 | |
| SCHEMBL4619329 | 0.75 | PPARG (0.55) | PPARGEPHX2KMT2APPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026335-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE CO. (US) | 2006-04-11 | — | — | US | disclosed |
| US-20050171158-A1 | Melanocortin receptor ligands | EBETINO FRANK H (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1499588-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20030236230-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2003-12-25 | — | — | US | disclosed |
| WO-2003093234-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171158-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | PPARG 914/4885EPHX2 1759/4885KMT2A 383/4885 |
| US-20030236230-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | PPARG 1081/4885EPHX2 1579/4885KMT2A 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.