Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713444 | 1.00 | PPARG (0.71) | PPARGEPHX2CYP1A2PPARAKMT2A | |
| Hydrochloric Acid SCHEMBL9239573 | 0.98 | PPARG (0.69) | PPARGEPHX2CYP1A2PPARAKMT2A | |
| SCHEMBL4663230 | 0.92 | CYP1A2 (0.65) | PPARGEPHX2CYP1A2PPARAKMT2A | |
| SCHEMBL9577446 | 0.86 | PPARG (0.56) | PPARGEPHX2CYP1A2PPARAKMT2A | |
| SCHEMBL8663107 | 0.85 | PPARG (0.55) | PPARGEPHX2CYP1A2PPARAKMT2A | |
| SCHEMBL3876493 | 0.83 | CYP1A2 (0.59) | PPARGEPHX2CYP1A2PPARAPPARD | |
| SCHEMBL6379983 | 0.83 | CYP1A2 (0.59) | PPARGEPHX2CYP1A2PPARAPPARD | |
| SCHEMBL11529738 | 0.83 | CYP1A2 (0.59) | PPARGEPHX2CYP1A2PPARAPPARD | |
| SCHEMBL3661382 | 0.83 | CYP1A2 (0.59) | PPARGEPHX2CYP1A2PPARAPPARD | |
| SCHEMBL265063 | 0.82 | CYP1A2 (0.83) | PPARGCYP1A2PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4253935-A | — | — | None | — | — | JP | disclosed |
| US-8815935-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-25 | — | — | US | disclosed |
| US-6365398-B1 | REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| JP-H04253935-A | PRODUCTION OF 2-(4-CHLORPHENYL)-3-METHYLBUTYRIC ACID | HOECHST AG | 1992-09-09 | — | — | JP | disclosed |
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | PPARG 2042/4885EPHX2 2534/4885CYP1A2 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.