Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840449 | 0.99 | DRD2 (0.45) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5512309 | 0.94 | DRD2 (0.49) | DRD2ADRA1A | |
| SCHEMBL5515953 | 0.93 | DRD2 (0.49) | DRD2ADRA1A | |
| SCHEMBL5519670 | 0.89 | KCNH2 (0.48) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5517902 | 0.88 | DRD2 (0.54) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5512917 | 0.88 | DRD2 (0.47) | DRD2ADRA1A | |
| SCHEMBL5515533 | 0.88 | KCNH2 (0.47) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5514892 | 0.88 | DRD2 (0.54) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5508650 | 0.87 | DRD2 (0.47) | DRD2ADRA1A | |
| SCHEMBL5517914 | 0.82 | DRD2 (0.50) | DRD2ADRA1AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199135-B2 | Substituted alkyl amido piperidines | H. LUNDBECK A/S (DK) | 2007-04-03 | — | — | US | disclosed |
| US-7199135-B2 | Substituted alkyl amido piperidines | H. LUNDBECK A/S (DK) | 2007-04-03 | — | — | US | disclosed |
| US-7105544-B2 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |